论文部分内容阅读
目的了解广州市人群流行性脑脊髓膜炎(简称流脑)的发病和带菌、抗体水平情况。方法病例个案调查采用统一调查表统计分析。人群采用横断面研究、整群抽样方法。结果2004年12月至2005年4月,广州市共发生流脑55例(其中民工及其子女占87.27%(48/55)、死亡2例(为民工),发病率为7.48/10万,病死率为3.6%。大学城工地民工带菌率(11.32%)明显高于广州市一般人群(1.92%)及大学城在校大学生(0.68%,!2=37.5412,P<0.001)。在大学城在校学生、大学城工地民工中注射流脑疫苗,免疫两周后抗体阳性率为93.82%(167/178),抗体阳性率明显高于免疫前(!2=85.6148,P<0.001)。结论广州市流动人口对A群流脑免疫力低,人群流脑菌苗接种率低,提示今后应在流动人群聚集地开展流脑菌苗接种,以提高其免疫水平。
Objective To understand the incidence, carriage and antibody level of epidemic cerebrospinal meningitis (referred to as meningitis) in Guangzhou. Methods Case investigation using a unified questionnaire statistical analysis. Cross-sectional study of population, cluster sampling method. Results From December 2004 to April 2005, there were 55 cases of meningitis in Guangzhou (87.27% (48/55) migrant workers and their children and 2 deaths (migrant workers), the incidence was 7.48 / 100 000, The case fatality rate was 3.6% in the university town laborers (11.32%), which was significantly higher than that of the Guangzhou general population (1.92%) and college students in university town (0.68%, 2 = 37.5412, P <0.001) The positive rate of antibody was 93.82% (167/178) in two weeks after immunization, and the positive rate of antibody was significantly higher than that before immunization (2 2 = 85.6148, P <0.001) .Conclusion The low population immunity of migrant population in Group A and the low population coverage of meningococcal vaccine in migrant population suggest that in future, meningococcal vaccine should be vaccinated in floating population to improve its immunization level.