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强烈化疗使成人急性淋巴细胞白血病(ALL)的完全缓解率(CR)明显提高,但其5年无病生存率(LFS)在不同研究单位报道的差异很大。通常认为这种差异与病人的特性和治疗强度有关。本文对50例成人原发性ALL的强烈化疗和每个细胞毒药物的平均剂量进行了回顾性研究。研究组病人的中数年龄28岁;男性27例,女性23例;白细胞>30×
Intense chemotherapy resulted in a significant improvement in complete remission (CR) of adult acute lymphoblastic leukemia (ALL), but its five-year disease-free survival (LFS) varied widely across studies. This difference is generally considered to be related to patient characteristics and treatment intensity. In this article, we performed a retrospective study of the intensive chemotherapy in 50 adult primary ALL patients and the average dose of each cytotoxic drug. The median age of the study group was 28 years; 27 males and 23 females; and white blood cells> 30x