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目的:探讨前哨淋巴结活检(sentinel lymph node biopsy,SLNB)预测老年口腔鳞癌患者颈部淋巴结转移的价值及提高病理准确性的方法。方法:对18例临床及影像学检查阴性的老年口腔鳞癌患者,采用1%美兰示踪定位识别前哨淋巴结,随后行全颈淋巴结清扫,将SLN做连续病理切片检查。结果:18例患者中检出SLN14例,其中13例的SLN能准确预测颈部淋巴结的转移状况。结论:应用美兰能准确定位SLN,前哨淋巴结连续病理切片活检结果,能准确预测颈部淋巴结的转移状况,具有潜在的临床应用价值。
Objective: To investigate the value of sentinel lymph node biopsy (SLNB) in prediction of cervical lymph node metastasis in elderly patients with oral squamous cell carcinoma and to improve the accuracy of pathology. Methods: Seventy patients with clinical and imaging negative elderly squamous cell carcinoma of oral squamous cell carcinoma were identified by 1% Meilan tracing for sentinel lymph node dissection, followed by complete cervical lymph node dissection. Serial SLN was used for pathological examination. Results: Among the 18 patients, 14 cases of SLN were detected, of which 13 cases of SLN could accurately predict the metastasis of cervical lymph nodes. Conclusion: The application of Meilan to accurately locate the SLN, the results of SLN biopsy can accurately predict the metastasis of cervical lymph nodes, and has potential clinical value.