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[目的]观察康复新及奥美拉唑联合运用治疗难治性胃食管反流病(GERD)的疗效。[方法]将难治性GERD50例随机分为2组,A组于清晨空腹及晚上睡前服用奥美拉唑20mg,康复新10ml,3次/d;B组用奥美拉唑,用法同A组,2组疗程均为8周。疗程结束后,复查胃镜,观察比较食管炎及反流等症状的改善程度。[结果]A组,临床症状总有效率84.0%,B组为56.0%(P<0.05);胃镜检查评价,A组总有效率为96.0%,B组为72.0%(P<0.05)。[结论]康复新联合奥美拉唑治疗GERD有较好的疗效。
[Objective] To observe the curative effect of rehabilitation and omeprazole in the treatment of refractory gastroesophageal reflux disease (GERD). [Method] 50 cases of refractory GERD were randomly divided into 2 groups. Group A received 10 mg omeprazole and 10 ml rehabilitation 3 times daily before going to bed in the early morning and fasting at night. Group B used omeprazole, Group A, two groups of treatment were 8 weeks. After the end of treatment, review gastroscopy, observe and compare esophagitis and reflux and other symptoms of improvement. [Results] In group A, the total effective rate of clinical symptoms was 84.0% in group B and 56.0% in group B (P <0.05). The total effective rate in group A was 96.0% and in group B was 72.0% (P <0.05). [Conclusion] Rehabilitation combined with omeprazole has a good curative effect in the treatment of GERD.