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目的 :研究孕激素对女性生殖道沙眼衣原体 (Chalmycliatrachomatis,CT)感染治疗的影响。方法 :2 0 4例女性下生殖道CT感染者按避孕措施分组 :Ⅰ组 :带铜 /前列腺素的IUD组 ;Ⅱ组 :复方短效避孕药组 ;Ⅲ组 :单孕激素探亲避孕药组 ,如孕三烯酮、炔诺酮等 ;Ⅳ组 :皮埋组。分别于 1d、2d、8d、9d口服希舒美 1g、0 .5g、1g、0 .5g ,停药 3W、2 4W复诊。结果 :①停药 3W初次治愈率 :Ⅰ组 87% ( 87/1 0 0 ) ,Ⅱ组 87.1 8% ( 34/39) ,Ⅲ组 88.46% ( 2 3/2 6) ,Ⅳ组 87.1 8% ( 34/39) ,激素避孕药组 (Ⅱ +Ⅲ +Ⅳ ) 87.5 % ( 91 /1 0 4 ) ,各组间差异均无显著性 ,P >0 .0 5。②停药 2 4W后感染复发率 :Ⅰ组 1 0 .34% ( 9/87)低于激素避孕药组(Ⅱ +Ⅲ +Ⅳ )组 2 7.47( % ) ( 2 5 /91 ) ,χ2 =8.44,P <0 .0 1 ,差异显著 ;Ⅱ组 1 4.71 % ( 5 /34)低于Ⅲ组 39.1 3% ( 9/2 3) ,χ2 =4.42 ,P <0 .0 5 ,差异显著 ;Ⅳ组 32 .2 5 % ( 1 1 /34)与Ⅱ组、Ⅲ组的差异均无显著性 ,P >0 .0 5。③继发盆腔炎发生率 ,Ⅰ组 5 % ( 5 /1 0 0 )低于激素避孕组 (Ⅱ +Ⅲ +Ⅳ ) 30 .77% ,( 32 /1 0 4 ) ,χ2 =2 2 .80 ,P <0 .0 1 ,差异显著 ;Ⅱ组 1 7.95 % ( 7/39)低于Ⅲ组 46.1 5 % ( 1 2 /2 6) ,χ2 =6.0 0 ,P <0 .0 5 ,差异显著 ;Ⅳ组 3
Objective: To study the effect of progestin on female genital Tract Chlamydia trachomatis (Chalmycliatrachomatis, CT) infection. METHODS: Twenty-four female genital CT-infected women were divided according to the method of contraception: group I: copper-prostaglandin IUD group; group II: compound short-acting contraceptive group; group III: , Such as gesthenone, norethindrone, etc .; Ⅳ group: skin buried group. Respectively, 1d, 2d, 8d, 9d oral Xishuomi 1g, 0.5g, 1g, 0.5g, withdrawal 3W, 24W referral. Results: ① The initial cure rate of 3W withdrawal was 87% (87/1 0 0) in group I, 87.1% (34/39) in group Ⅱ, 88.46% (2 3/26) in group Ⅲ, 87.1% (34/39), and 87.5% (91/104) of hormonal contraceptive group (Ⅱ + Ⅲ + Ⅳ). There was no significant difference between the two groups (P> 0.05). (2) The recurrence rate after discontinuation of 2 4 W was lower in group Ⅰ (10.44%, 9/87) than that in group Ⅱ + Ⅲ + Ⅳ (2 7.47%, 2/91) 8.44, P <0.01, the difference was significant. In group Ⅱ, 4.71% (5/34) was lower than 39.1% (9/2 3) in group Ⅲ, χ2 = 4.42, P <0.05, There was no significant difference between group Ⅳ and group Ⅱ, group Ⅲ (P <0.05). ③ The incidence of secondary pelvic inflammatory disease in group Ⅰ was lower than that in group Ⅰ (30%), (30%) and (32/104), respectively , P <0.01, the difference was significant; in group Ⅱ, 1 7.95% (7/39) was lower than that in group Ⅲ (46.1 5% (12/2 6), χ2 = 6.0 0, P <0.05) Group Ⅳ