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目的 :研究微量胶囊法14 C -尿素呼气试验 (UBT)诊断幽门螺旋杆菌 (HP)的临床应用价值。方法 :对 3 5 2例因消化道症状就医的患者同时进行14 C -尿素呼气试验 (UBT)、快速尿素酶 (RUT)及病理组织学检查。将上述三种方法的灵敏度、特异度、准确度、阳性预测值、阴性预测值加以比较。其中 67例患者经抗HP治疗后复查14 C -尿素呼气试验。结果 :14 C -尿素呼气试验的灵敏度、特异度、准确度、阳性预测值、阴性预测值高于快速尿素酶及病理组织学。经抗HP治疗后的患者大部分HP检查阴性 ,阳性者其14 CDPM值也大为降低。结论 :14 C -尿素呼气试验具有安全、简便、可靠、无交叉感染及无创伤性等优点
Objective: To study the clinical value of 14C urea breath test (UBT) in the diagnosis of Helicobacter pylori (HP) by microencapsulation. Methods: Thirty - five patients with gastrointestinal symptoms were treated simultaneously with 14 C - urea breath test (UBT), rapid urease (RUT) and histopathological examination. The above three methods of sensitivity, specificity, accuracy, positive predictive value, negative predictive value to be compared. Sixty-seven of these patients underwent 14 C-urea breath test after anti-HP treatment. Results: The sensitivity, specificity, accuracy, positive predictive value and negative predictive value of 14 C - urea breath test were higher than those of rapid urease and histopathology. Most HP patients who were treated with anti-HP were negative for the HP test and their 14 CDPM values were also significantly reduced. Conclusion: 14 C - urea breath test has the advantages of safety, simplicity, reliability, no cross infection and noninvasiveness