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目的:探讨高同型半胱氨酸血症对高血压患者心脏重构的影响。方法:选取2016年9月-2017年3月我院就诊高血压患者104例,其中正常同型半胱氨酸组52例、高同型半胱氨酸组52例,记录两组心脏彩超结果,比较两组左心房内径(LA)、左心室舒张末期内径(LVED)、室间隔厚度(IVS)、左心室后壁厚度(LVPW)、左心室质量(LVM)、左室心肌质量指数(LVMI)、右心房内径(RA)值。结果:正常同型半胱氨酸组与高同型半胱氨酸组比较,LA(3.81±0.45 vs 3.57±0.38)、LVED(4.84±0.27 vs 4.68±0.27)、IVS(0.88±0.1 vs 0.82±0.09)、LVPW(0.85±0.09 vs 0.8±0.07)、LVW(163.77±36.88 vs 143.58±32.56)、LVWI(95.54±25.3 vs 83.51±19.64)、RV(2.03±0.2 vs 1.94±0.11),差异均有统计学意义。结论:高同型半胱氨酸血症与高血压患者心脏重构相关。
Objective: To investigate the effect of hyperhomocysteinemia on cardiac remodeling in hypertensive patients. Methods: From September 2016 to March 2017, 104 cases of hypertensive patients admitted to our hospital were selected. Among them, 52 cases were in normal homocysteine group and 52 cases in homocysteine group. The results of echocardiography were recorded and compared Left atrium diameter (LV), left ventricular diastolic dimension (LVED), left ventricular posterior wall thickness (LVPW), left ventricular mass (LVM), left ventricular mass index Right atrial diameter (RA) value. Results Compared with high homocysteine group, the normal homocysteine group showed significant differences in LA (3.81 ± 0.45 vs 3.57 ± 0.38), LVED (4.84 ± 0.27 vs 4.68 ± 0.27), IVS (0.88 ± 0.1 vs 0.82 ± 0.09 ), LVPW (0.85 ± 0.09 vs 0.8 ± 0.07), LVW (163.77 ± 36.88 vs 143.58 ± 32.56), LVWI (95.54 ± 25.3 vs 83.51 ± 19.64) and RV (2.03 ± 0.2 vs 1.94 ± 0.11) Significance of learning. Conclusion: Hyperhomocysteinemia is associated with cardiac remodeling in hypertensive patients.