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探讨深部痰液粒细胞集落刺激因子 (G- CSF)测定对毛细支气管炎合并细菌感染的诊断价值。方法 :采用双抗体夹心 EL ISA法 ,检测 74例单纯毛细支气管炎和 2 7例毛细支气管炎合并细菌感染患儿的深部痰液 G- CSF阳性率 ,并对两组患儿进行痰细菌学培养和病毒病原学检测。结果 :两组 G- CSF阳性率和细菌培养阳性率差异均有显著性 (P<0 .0 1和 P<0 .0 5 ) ,病毒病原学检出率无统计学意义。结论 :痰液G- CSF检测是毛细支气管炎并发细菌感染的敏感性指标。
To investigate the diagnostic value of deep sputum granulocyte-colony stimulating factor (G-CSF) in the diagnosis of bronchiolitis complicated with bacterial infection. Methods: The positive rate of G-CSF in deep sputum in 74 cases of simple bronchiolitis and 27 cases of bronchiolitis with bacterial infection was detected by double-antibody sandwich ELISA, and sputum bacteriological culture And viral etiology test. Results: The positive rate of G-CSF and the positive rate of bacterial culture were significantly different between the two groups (P <0.01 and P <0.05). The detection rate of viral etiology was not statistically significant. Conclusion: Sputum G-CSF test is a sensitive indicator of bacterial infection in patients with bronchiolitis.