Acute histopathological responses and long-term behavioral outcomes in mice with graded controlled c

• 作 者: Si-Yi Xu Min Liu Yang Gao Yang
• 机 构: DepartmentofNeurosurgery,DepartmentofNeurosurgery
• 出 处: 中国神经再生研究:英文版
• 发表日期: 2019年6期
• 关键词: nerve REGENERATION TRAUMATIC brain INJURY controlled cortical impact HISTOPATHOL
• 基金项目: the National Natural Science Foundation of China,No.81771332,81571184,81070990(all to CLZ),the Shanghai Key Medical Discipline for Critical Care Medicine of China,No.2017zz02017(to CLZ),the Key Discip

While animal models of controlled cortical impact often display short-term motor dysfunction after injury,histological examinations do not show severe cortical damage.Thus,this model requires further improvement.Mice were subjected to injury at three seve