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目的探讨采用阿魏酸钠、复方谷氨酰胺与双歧四联活菌片治疗溃疡性结肠炎的疗效。方法对确诊患者随机分为对照组和治疗组,对照组常规给予半流质饮食,经纠正水电解质紊乱,口服柳氮磺吡啶1 g(qid)连用2周;阿魏酸钠治疗组在一般治疗基础上,给予注射用阿魏酸钠02 g 加入250 mL 5%葡萄糖液静滴,每天1次,连用2周。根据用药前后症状改善情况、肝肾功能、C 反应蛋白、免疫球蛋白、纤维结肠镜或钡剂灌肠的变化来评定疗效。结果治疗组及对照组的总有效率分别为92.3%、67.9%,两组比较差异有显著性(P<0.05)。结论在常规治疗基础上加用阿魏酸钠、复方谷氨酰胺、双歧四联活菌片可以较快控制病情,可减少复发,无不良反应,是治疗溃疡性结肠炎一种较好的方案。
Objective To investigate the curative effect of treating ulcerative colitis with sodium ferulate, compound glutamine and bifidobacterium quadriceps. Methods The patients diagnosed were randomly divided into control group and treatment group. The control group was given semi-liquid diet routinely, corrected the water and electrolyte disturbance, oral qs sulfasalazine 1 g (qid) for 2 weeks; sodium ferulate group in general treatment On the basis of giving sodium ferulate for injection 02 g added 250 mL 5% glucose solution intravenously once daily for 2 weeks. According to the symptoms before and after treatment, liver and kidney function, C-reactive protein, immunoglobulin, colonoscopy or barium enema changes to assess the efficacy. Results The total effective rates of the treatment group and the control group were 92.3% and 67.9%, respectively, with significant difference between the two groups (P <0.05). Conclusion The addition of sodium ferulate, compound glutamine and bifidobacterium viable tablets can control the disease faster, reduce the relapse and have no adverse reactions. It is a better treatment for ulcerative colitis Program.