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目的:观察中药对高血铅致反复呼吸道感染患儿的治疗作用。方法:将120例高血铅致反复呼吸道感染患儿分为中药治疗组和西药对照组各60例,观察两组治疗前后的血铅变化及呼吸道感染发作频率。结果:血铅浓度中药组治疗前为(172.42±38.57)μg/L,治疗后为(62.15±37.62)μg/L;对照组治疗前为(173.27±37.68)μg/L,治疗后为(152.42±36.24)μg/L,两组治疗前后血铅浓度变化差异有统计学意义(P≤0.01)。呼吸道感染发作平均间隔天数治疗组为(31.94±5.78)天,对照组为(12.67±6.33)天,治疗组明显优于对照组(P<0.05)。经过2个疗程的治疗,治疗组总有效率为90.00%,对照组总有效率为43.33%,两组差异有统计学意义(P<0.05)。结论:中药可以排除患儿体内铅毒,增强机体免疫功能,改善高血铅症状,降低呼吸道感染几率。
Objective: To observe the therapeutic effect of traditional Chinese medicine on children with recurrent respiratory tract infection caused by high blood lead. Methods: A total of 120 children with recurrent respiratory tract infections caused by high blood lead were divided into two groups: 60 cases in TCM group and 60 cases in Western medicine group. Changes of blood lead and respiratory tract infection frequency were observed before and after treatment. Results: The level of blood lead was (172.42 ± 38.57) μg / L before treatment and (62.15 ± 37.62) μg / L before treatment in the control group, and was (173.27 ± 37.68) μg / L before treatment and 152.42 ± 36.24) μg / L, there was significant difference between the two groups before and after treatment (P≤0.01). The average number of days of respiratory tract infection was (31.94 ± 5.78) days in treatment group and (12.67 ± 6.33) days in control group, which was significantly better than that in control group (P <0.05). After two courses of treatment, the total effective rate was 90.00% in the treatment group and 43.33% in the control group, with significant difference between the two groups (P <0.05). Conclusion: Chinese medicine can rule out lead poisoning in children, enhance immune function, improve symptoms of high blood lead and reduce the risk of respiratory infection.