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Ph_3P/CF_3CCl_3与醛在室温下一锅反应生成三氟甲基取代的烯烃RCH=CClCF_3(3)。芳香醛及α,β-不饱和醛的反应显示高度立体选择性,给出Z式异构体。而饱和脂肪醛的反应立体选择性较低,Z与E式异构体的比例为2:1至3:1。反应可能是经由叶立德Ph_3P-CClCF_3的Wittig型反应。本工作表明,Pa_3P/CF_3CCl_3可以作为在十分温和的条件下向有机分子中引入=CClCF_3结构单元的方便试剂。
Ph_3P / CF_3CCl_3 reacts with the aldehyde at room temperature to form the trifluoromethyl-substituted olefin RCH = CClCF_3 (3). The reaction of aromatic aldehydes and [alpha], [beta] -unsaturated aldehydes shows a high degree of stereoselectivity, giving the Z isomer. The reaction of saturated aliphatic aldehydes with low stereoselectivity, Z and E isomer ratio of 2: 1 to 3: 1. The reaction may be Wittig-type reaction via ylide Ph_3P-CClCF_3. This work shows that Pa_3P / CF_3CCl_3 can be used as a convenient reagent for introducing CClCF_3 structural units into organic molecules under very mild conditions.