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目的：研究产前综合护理干预对预防产妇出现产后抑郁症的实际效果。方法：我院接收的212例产前检查孕妇，对照组106例进行常规产科护理，实验组106例进行产前综合护理，分娩4周后使用爱丁堡产后抑郁量表评价产妇的抑郁情况。结果：对照组进行常规产科护理后产妇爱丁堡产后抑郁量表评分为12.26±2.15，实验组进行产前综合护理后产妇爱丁堡产后抑郁量表评分为8.97±1.36。对照组进行常规产科护理后出现20例抑郁症患者，产后抑郁症发生率为18.87%；实验组进行产前综合护理后出现4例抑郁症患者，产后抑郁症发生率为3.77%。结论：产前综合护理可以有效降低孕妇产后抑郁症的发生率，保证生育质量，值得推广。“,”Objective To study the actual effects of postpartum depression occurs prenatal comprehensive nursing intervention for the prevention of maternal.Methods The hospital received 212 cases of prenatal care for pregnant women, 106 cases in the control group routine obstetric care, the experimental group were 106 cases of comprehensive prenatal care, use of the Edinburgh Postnatal Depression Scale Evaluation of maternal depression four weeks after childbirth.Results In the control group, routine obstetric care maternal EPDS score was 12.26 ± 2.15, after a comprehensive experimental group prenatal care maternal EPDS score was 8.97 ± 1.36. 20 cases of depression patients in the control group routine obstetric care, postpartum depression incidence was 18.87%; 4 cases of patients with depression after a comprehensive experimental group prenatal care, postpartum depression rate was 3.77%.Conclusion Comprehensive prenatal care can effectively reduce the incidence of maternal postpartum depression, to ensure reproductive quality, worthy of promotion.