论文部分内容阅读
先天性巨结肠(HD)的诊断一般是根据X线、肛门直肠测压和直肠活检.但X线表现在新生儿期不尽可靠;肛门直肠测压可显示内括约肌松弛反射缺如,对诊断有裨益,但有时难以取得患儿合作;Swenson式直肠全层活检需要用全麻,技术上有一定危险.近年发展了直肠吸吮活检组织化学染色法,是对诊断的一大进步,尤其对新生儿病例,且不需麻醉,罕有并发症.直肠活检染色检查乙酰胆碱酯酶(AChE)活力,HD时可在固有膜和粘膜肌层观察到显著的神经纤维,同时缺乏节
Diagnosis of Hirschsprung’s disease (Hirschsprung’s disease) is usually based on X-ray, anorectal manometry and rectal biopsy, but X-ray findings are not reliable in the neonatal period. Anorectal manometry shows absence of internal sphincter relaxation reflexes, There are benefits, but sometimes difficult to obtain cooperation in children; full-thickness biopsy Swenson rectal need general anesthesia, there is a certain risk .In recent years, the development of rectal sucking biopsy histochemical staining is a great improvement in diagnosis, especially for freshmen Children were not required anesthesia and rare complication.Rectal biopsy was performed to examine AChE activity and significant neurofibrils were observed in the lamina propria and mucosal muscle layers at HD,