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作者对27例胸膜渗液病人同时进行了周围血和胸水淋巴细胞测定,其中特异性渗液17例(恶性肿瘤12例,结核病3例及胶原病2例),非特异性渗液10例(肺炎无菌性渗液1例,肺栓塞2例及特发性7例)。采用双重玫瑰花结方法测定胸腺淋巴细胞(TLY)和来自骨髓带有Fc受体而无吞噬作用的淋巴细胞(Fc-LY)。各种病因引起的胸水与周围血中T-LY及Fc-LY的百分率没有差异。特异性胸膜渗液(恶性肿瘤、结核病及胶原病)病人胸水中T-LY绝对数大于非特异性渗液病人(P<0.002)。10例非特异性渗液病人中8例周围血T-LY绝对数在正常范围,而17例特异性渗液中有16例周围血T-LY值低于正常(正常范围750～2,400/mm~3),仅1例正常,两者差异显著(P<0.002)。12例恶性肿瘤中的10例,所有3例结核病及2例胶原病的胸水与周围血T-LY绝对数的比例>1,指示在胸水中
The authors of the 27 cases of pleural effusion in patients with simultaneous determination of peripheral blood and pleural fluid lymphocytes, including 17 cases of specific exudate (12 cases of malignant tumors, 3 cases of tuberculosis and collagen disease in 2 cases), 10 cases of non-specific exudate (pneumonia 1 case of sterile exudate, 2 cases of pulmonary embolism and idiopathic 7 cases). Thymic lymphocytes (TLY) and lymphocytes (Fc-LY) from the bone marrow with Fc receptors without phagocytosis were determined by the double rosette method. There was no difference in the percentage of T-LY and Fc-LY in pleural effusion and peripheral blood due to various causes. Specific pleural effusion (malignancy, tuberculosis and collagen disease) pleural effusion in patients with absolute T-LY non-specific exudate patients (P <0.002). The absolute number of T-LY in the peripheral blood of 8 patients with nonspecific exudate was within the normal range, whereas the T-LY values of peripheral blood in 16 of 17 patients with exudate were lower than normal (normal range: 750-2,400 / mm ~ 3), only one case of normal, significant difference between the two (P <0.002). Ten of 12 malignant tumors showed a> 1 ratio of absolute numbers of T-LY in pleural effusion to peripheral blood in all three cases of tuberculosis and two cases of collagen disease,