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目的:观察中西医结合治疗急性脑梗死的临床疗效。方法:选择发病72小时内患者122例,随机分为2组。对照组58例,予西医扩血管、抗血小板聚集、保护脑神经等常规治疗,连续治疗14天。治疗组64例,在对照组治疗的基础上,予以化痰祛瘀消梗汤治疗,连续治疗14天。治疗前及治疗后第7天、第14天分别进行神经功能缺损程度评分、临床疗效和血液流变学评价。结果:总有效率治疗组90.6%,对照组84.5%,2组临床疗效比较,差异有显著性意义(P<0.05)。2组治疗第7、14天后的神经功能缺损程度评分较治疗前均有所改善(P<0.05);治疗14天与7天比较,差异有非常显著性意义(P<0.01)。治疗14天后2组比较,差异有显著性意义(P<0.05)。治疗组血小板聚集率、纤维蛋白原含量治疗后较治疗前降低(P<0.05)。2组治疗后纤维蛋白原含量比较,差异有显著性意义(P<0.05)。结论:中西医结合治疗较单纯西医综合治疗效果好,能降低致残率,加快肢体功能的恢复,提高临床疗效,改善预后。
Objective: To observe the clinical efficacy of integrated traditional Chinese and western medicine in the treatment of acute cerebral infarction. Methods: 122 patients were selected within 72 hours of onset, were randomly divided into two groups. Control group of 58 cases, to Western vasodilator, anti-platelet aggregation, protection of the brain and other conventional treatment, continuous treatment for 14 days. The treatment group of 64 cases, on the basis of the control group, to be phlegm stasis Chiaoji Tang treatment, continuous treatment for 14 days. The score of neurological deficit, clinical efficacy and hemorheology were evaluated before treatment and 7 days and 14 days after treatment respectively. Results: The total effective rate was 90.6% in the treatment group and 84.5% in the control group. There was significant difference between the two groups in clinical curative effect (P <0.05). The score of neurological deficit in the two groups after treatment for 7 and 14 days was significantly improved compared with those before treatment (P <0.05). There was significant difference between the 14th and 7th days (P <0.01). After 14 days of treatment, there was significant difference between the two groups (P <0.05). The platelet aggregation rate and fibrinogen content of the treatment group were lower than those before treatment (P <0.05). There was significant difference in fibrinogen content between the two groups after treatment (P <0.05). Conclusion: The combination of TCM and Western medicine is better than that of simple Western medicine, which can reduce the morbidity, accelerate the recovery of limb function, improve the clinical curative effect and improve the prognosis.