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特发性血小板减少性紫癜(ITP)是一组原因不明的综合征,其特征表现为外周血中的血小板减少、紫癜、血小板的存活时间缩短及骨髓中巨核细胞代偿性增生。血小板的生成是有效的,但有时可以生成巨血小板。1951年Harrington等首先提出本病的免疫学性质,认为本病同由自身抗红细胞抗体引起的溶血性贫血相似,是由自身的抗血小板抗体引起的血小板减少,因此,本病也可称为免疫性血小板减少性紫癜。但是,ITP的患者中只有90%的病人抗血小板抗体是增高的。为此,Karptkin
Idiopathic thrombocytopenic purpura (ITP) is a group of unexplained syndrome characterized by thrombocytopenia in peripheral blood, purpura, shortened survival of platelets, and compensatory hyperplasia of megakaryocytes in bone marrow. Platelet production is effective, but sometimes it can generate giant platelets. Harrington first proposed in 1951, the immunological nature of the disease, that the disease with its own anti-red blood cell antibodies caused by hemolytic anemia is similar to their anti-platelet antibodies caused by thrombocytopenia, therefore, the disease can also be called immune Thrombocytopenic purpura. However, only 90% of patients with ITP have elevated antiplatelet antibodies. To this end, Karptkin