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多器官功能衰竭(MOF)的病因、病理十分复杂,临床表现多样,预后极其严重。是儿科急救医学的重要组成部分。现对我科近十年住院死亡病例中149例MOF资料分析如下。 临床资料 男108例,女41例;年龄～1月84例,～1岁31例。～3岁15例,～7岁6例,～14岁13例。根据全国儿科危重症学术研讨会所订诊断标准(实用儿科杂志,1987:8:61):(1)呼吸衰竭:PaO_2<6.67kPa,PaCO_2>6.67kPa;(2)心力衰竭:心率>160次/分(幼儿)或>180次/分(婴儿),呼吸频率>60次/分,肝肿大,心脏增大;(3)肾衰:少尿或无尿,血Cr>176.8μmol/L,BUN>7.14μmol/L,酸中毒、高血钾;(4)肝衰;迅速出现黄疸,肝脏短期内增大1cm以上。肝功能损害,SGPT高于正常2倍以上;(5)胃肠功能衰竭:严重腹胀、肠麻痹、胃肠出血需输血者;(6)中枢神经系统衰竭;昏迷、脑疝、中枢性呼吸衰竭。(7)DIC:出血、溶血、栓
Multiple organ failure (MOF) etiology, pathology is very complex, diverse clinical manifestations, the prognosis is extremely serious. Pediatric emergency medicine is an important part. 149 cases of hospitalized deaths in recent years in our department MOF data analysis is as follows. Clinical data of 108 males and 41 females; age ~ January 84 cases, ~ 1 year old in 31 cases. ~ 3 years old in 15 cases, ~ 7 years in 6 cases, ~ 14 years in 13 cases. According to the National Diagnostic Criteria for Pediatric Critical Care (Practical Journal of Pediatrics 1987: 8: 61): (1) respiratory failure: PaO_2 <6.67kPa, PaCO_2> 6.67kPa; (2) heart failure: heart rate> 160 beats / (3) Renal failure: oliguria or anuria, blood Cr> 176.8μmol / L, blood pressure less than 60 beats / min, BUN> 7.14μmol / L, acidosis, hyperkalemia; (4) liver failure; rapid jaundice, the liver increased more than 1cm in the short term. Liver function damage, SGPT higher than normal 2 times above; (5) gastrointestinal failure: severe abdominal distension, intestinal paralysis, gastrointestinal bleeding need transfusion; (6) central nervous system failure; coma, hernia, central respiratory failure . (7) DIC: bleeding, hemolysis, suppository