【摘 要】
：
Cytokines (such as IL-6, TNF-α, and IFN-γ) were considered as important factors during the onset of atuoimmune disease, such as rheumatoid arthritis and mult
【机 构】
：
Department of Pharmacology,Gifu Phannaceutical University,Gifu,Japan,Department of Pharmacology,Gifu
【出 处】
：
Acta Pharmacologica Sinica
论文部分内容阅读
Cytokines (such as IL-6, TNF-α, and IFN-γ) were considered as important factors during the onset of atuoimmune disease, such as rheumatoid arthritis and multiple sclerosis, but the early response of cytokines after immunization is still unclear. In the present experiment, we examined the changes of mRNA levels of several cytokines, inducible nitric-oxide synthase (iNOS) in hypothalamus, pituitary and spinal cord of DA rats 3 d after MBP immunization to analysis the early cytokines response
Cytokines (such as IL-6, TNF-α, and IFN-γ) were considered as important factors during the onset of atuoimmune disease, such as rheumatoid arthritis and multiple sclerosis, but the early response of cytokines after immunization is still unclear. In the present experiment, we examined the changes of mRNA levels of several cytokines, inducible nitric-oxide synthase (iNOS) in hypothalamus, pituitary and spinal cord of DA rats 3 d after MBP immunization to analysis the early cytokines response
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