论文部分内容阅读
[目的]探讨氟西汀联合自拟理气和中汤治疗围绝经期功能性消化不良(MPFD)的临床疗效。[方法]89例患者随机分为对照组和观察组,对照组用氟西汀20mg,每日1次,晨服,治疗组在对照组基础上加用自拟中药理气和中汤每日1剂,分2次煎服。4周为1疗程。随访6个月的复发率。[结果]观察组治愈率43.75%,总有效率93.75%;对照组治愈率21.95%,总有效率73.17%。观察组明显优于对照组(P<0.05)。6个月后2组复发率比较,观察组8.33%,对照组38.46%,2组比较差异有统计学意义(P<0.01)。[结论]氟西汀联合理气和中汤对MPFD有良好的临床疗效。能够调节胃肠神经功能紊乱,促进胃肠蠕动及胃排空,降低胃的敏感性;调节中枢神经系统、缓解患者压力。
[Objective] To explore the clinical efficacy of fluoxetine in combination with self-made qi and soup in the treatment of peri-menopausal dyspepsia (MPFD). [Method] 89 patients were randomly divided into control group and observation group. The control group was treated with Fluoxetine 20mg, once daily, morning service, and treatment group on the basis of the control group Agent, sub-2 decoction. 4 weeks for a course of treatment. The recurrence rate was followed up for 6 months. [Results] The cure rate of the observation group was 43.75%, the total effective rate was 93.75%. The cure rate of the control group was 21.95%, the total effective rate was 73.17%. The observation group was significantly better than the control group (P <0.05). After 6 months, the recurrence rates in the two groups were significantly different (8.33% in the observation group and 38.46% in the control group). There was significant difference between the two groups (P <0.01). [Conclusion] Fluoxetine combined with Qi and Zhong Tang have good clinical curative effect on MPFD. Can regulate gastrointestinal disorders, promote gastrointestinal motility and gastric emptying, reduce gastric sensitivity; regulate the central nervous system, relieve stress in patients.