论文部分内容阅读
目的 探讨复发性卵巢上皮癌二次细胞减灭术的意义及可行性。方法62例复发性卵巢上皮癌接受了二次细胞减灭术。其中48例手术成功,14例仅做探查术。术式包括部分肠切除、肠修补、脾切除、残余大网膜切除及其它转移瘤切除。仅作探查术者是由于转移癌浸润大血管及胰十二指肠等重要脏器,肠系膜呈蜡肠状等。术后辅以铂剂为主的联合化疗。结果 残余瘤直径小于2cm的27例2年和5年存活率分别为40.7%及14.8%。残余瘤大于2cm的35例只有1例存活超过2年(2.9%)。结论 成功的二次肿瘤细胞减灭术能提高患者的存活率。术前作好检查筛去不适合手术病例会提高成功率。
Objective To investigate the significance and feasibility of secondary cytoreductive surgery for recurrent epithelial ovarian cancer. Methods 62 cases of recurrent epithelial ovarian cancer received cytoreductive surgery. Forty-eight cases were successfully surgically treated and 14 cases were only probed. Procedures include partial bowel resection, intestinal repair, splenectomy, residual omental resection and other metastases resection. Only for exploration who is due to metastatic cancer infiltration of blood vessels and other important organs such as the pancreatic duodenum, mesentery was waxy intestinal and so on. Postoperatively combined with platinum-based chemotherapy. Results The 2-year and 5-year survival rates of 27 cases with residual tumor diameter less than 2 cm were 40.7% and 14.8% respectively. Only one of the 35 patients with a residual tumor larger than 2 cm survived more than 2 years (2.9%). Conclusion The successful secondary cytoreductive surgery can improve the survival rate of patients. Preoperative check screen to go unsuitable for surgical cases will increase the success rate.