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目的观察氨来呫喏糊剂和益口含漱液两种方法治疗复发性口腔溃疡的临床效果。方法将我院自2008年9月～2010年4月收治的147例复发性口腔溃疡患者随机分为观察组(76例)和对照组(71例),观察组采用氨来呫诺糊剂局部涂布;对照组采用益口含漱液治疗。观察治疗后口腔溃疡局部症状改善情况。结果观察组总有效率为96.1%,对照组总有效率为70.4%,两组疗效比较有统计学差异(P<0.05)。观察组与治疗组治疗前与治疗后3d、5d溃疡疼痛VAS评分比较显示观察组缓解疼痛效果大于对照组,有统计学差异(P<0.05)。结论氨来呫喏糊剂治疗复发性口腔溃疡方法简单,局部症状改善明显,疼痛缓解快,远期疗效理想,值得临床推广。
Objective To observe the clinical effects of ammonia xanthine paste and Yikou gargle two methods for the treatment of recurrent oral ulcer. Methods A total of 147 patients with recurrent oral ulcer admitted to our hospital from September 2008 to April 2010 were randomly divided into observation group (76 cases) and control group (71 cases). The observation group was treated with amiloxannide paste locally The control group was treated with Yikou gargle. To observe the improvement of local symptoms of oral ulcer after treatment. Results The total effective rate was 96.1% in the observation group and 70.4% in the control group. There was significant difference between the two groups (P <0.05). The comparison of the VAS scores of pain ulcer in the observation group and the treatment group before and 3 days and 5 days after treatment showed that the pain relief effect of the observation group was greater than that of the control group (P <0.05). Conclusions Ammonia xanthine paste is a simple and effective method for the treatment of recurrent oral ulcer. The local symptoms are obviously improved and the pain is relieved quickly. The long-term curative effect is ideal and worthy of clinical promotion.