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应用经皮球囊肺动脉瓣成形术(PBPV)姑息治疗法洛四联症13例,其中男8例,女5例;平均年龄(3.7±2.1)岁。SaO_2由术前平均75.5％±4.3％上升至术后91.3％±4.7％(P<0.001),肺动脉/漏斗部压差由(27±2.78)mmHg下降至(3.95±8.21)mmHg(P<0.01),肺动脉瓣环大小与术前相仿(13mm±3.5mm vs 14mm±2.7mm,P>0.05)。随访(1～2)年,病情稳定,Sa O_2大多维持在85％左右,均接受外科手术。结果表明,PBPV对一些病例作为替代外科姑息手术治疗法洛四联症是可行的,为最终外科根治创造良好条件。
Thirteen patients with tetralogy of Fallot were treated with percutaneous balloon pulmonary valvuloplasty (PBPV), including 8 males and 5 females with a mean age of (3.7 ± 2.1) years. SaO_2 increased from 75.5% ± 4.3% preoperatively to 91.3% ± 4.7% postoperatively (P <0.001), while pulmonary artery / funnel pressure decreased from (27 ± 2.78) mmHg to (3.95 ± 8.21) mmHg ). The pulmonary valve annulus size was similar to preoperative (13mm ± 3.5mm vs 14mm ± 2.7mm, P> 0.05). Follow-up (1 ~ 2) years, stable condition, Sa O_2 mostly maintained at about 85%, were undergoing surgery. The results showed that PBPV was feasible in some cases as an alternative to surgical palliative surgery for tetralogy of Fallot, creating favorable conditions for the ultimate surgical cure.