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目的观察热毒宁注射液治疗毛细支气管炎的临床疗效。方法将106例患儿随机分为治疗组56例和对照组50例,在常规治疗基础上,对照组加用利巴韦林注射液静脉滴注,治疗组加用热毒宁注射液静脉滴注,观察两组患儿用药后症状及体征的改善情况,比较两组患儿的临床疗效。结果治疗组治愈率71.4%,总有效率92.9%,对照组治愈率52.0%,总有效率为64%,两组治愈率比较差异有统计学意义(χ2=4.01,P<0.05),两组总有效率比较差异有显著统计学意义(χ2=13.82,P<0.01),治疗组在主要临床症状、体征消失时间和总住院天数等方面均短于对照组,两组比较差异有统计学意义(P<0.01)。结论热毒宁注射液静脉滴注治疗毛细支气管炎疗效明显,无明显不良反应,值得临床推广。
Objective To observe the clinical efficacy of Renduining injection in the treatment of bronchiolitis. Methods 106 cases of children were randomly divided into treatment group 56 cases and control group 50 cases, on the basis of routine treatment, the control group plus ribavirin injection intravenous drip, the treatment group with Revinu injection intravenous drip Note, to observe the improvement of symptoms and signs of two groups of children after treatment, the clinical efficacy of two groups were compared. Results The cure rate was 71.4% and the total effective rate was 92.9% in the treatment group. The cure rate was 52.0% in the control group and the total effective rate was 64%. There was significant difference between the two groups in curative rate (χ2 = 4.01, P <0.05) The total effective rate was significantly different (χ2 = 13.82, P <0.01), the treatment group was shorter than the control group in the main clinical symptoms, signs of disappearance of time and the total number of days of hospitalization, the difference between the two groups was statistically significant (P <0.01). Conclusion Revedunin injection intravenous drip treatment of bronchiolitis obvious effect, no obvious adverse reactions, is worth clinical promotion.