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[目的]观察度洛西汀联合认知行为干预治疗胆汁反流性胃炎合并抑郁症患者的临床疗效。[方法]72例胆汁反流性胃炎合并抑郁症患者随机分为2组,2组患者均给予常规治疗,治疗组加用度洛西汀联合认知行为干预治疗。[结果]2组治疗后临床疗效、镜下表现及抑郁自评量表评分比较差异有统计学意义(P<0.05)。[结论]度洛西汀联合认知行为干预治疗胆汁反流性胃炎合并抑郁症患者临床疗效满意。
[Objective] To observe the clinical efficacy of duloxetine combined with cognitive behavioral intervention in the treatment of patients with bile reflux gastritis complicated with depression. [Methods] Seventy-two patients with bile reflux gastritis complicated with depression were randomly divided into two groups. The two groups were given conventional treatment. The treatment group was treated with duloxetine combined with cognitive behavioral intervention. [Results] The clinical curative effect, microscopic appearance and self-rating depression scale in two groups had significant difference (P <0.05). [Conclusion] The clinical efficacy of duloxetine combined with cognitive behavioral intervention in the treatment of patients with bile reflux gastritis complicated by depression is satisfactory.