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人群对分支杆菌的暴露增加时,结核菌素的反应率和反应强度也增加,如重复卡介苗(BCG)免疫即如此.提示如无减敏因素影响,分支杆菌负荷高者,结核菌素反应可以很高。结核菌素反应可评价人类对分支杆菌反应的遗传性调节,所以研究分支杆菌最大暴露时的皮试情况有重要意义。为此分析了有和无BCG免疫的新近发作肺结核患者结核菌素反应强度,以及治疗后反应的稳定性。受试者均为病史2年以上肺结核患者,并新近诊
The response rate and response intensity of tuberculin also increased as the population exposed to mycobacteria increased, as was the case with repeated BCG immunization, suggesting that if there is no desensitization, the mycobacterial load may be high, the tuberculin response may be High. The tuberculin reaction evaluates the genetic regulation of mycobacterial response in humans, so it is important to study the skin test at the time of maximum exposure to mycobacteria. For this reason, the intensity of tuberculin reaction in newly diagnosed tuberculosis patients with and without BCG immunization as well as the stability of the response after treatment were analyzed. Subjects were all patients with a history of more than 2 years with tuberculosis and were newly admitted