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目的探讨阿奇霉素治疗肺炎支原体感染致小儿过敏性咳嗽的临床疗效。方法选取2014年7月—2015年7月林州市人民医院收治的过敏性咳嗽患儿80例作为治疗组,按随机数字表法分为治疗A组与治疗B组,各40例。另选取同期林州市人民医院收治的普通呼吸道感染患儿80例作为对照组。治疗B组患儿予以常规方法治疗,治疗A组患儿予以止咳解痉药联合大环内酯类药物治疗。观察3组患者MP-Ig M测定结果、治疗A组与治疗B组患儿临床疗效及不良反应发生情况。结果治疗组患儿MP-Ig M阳性率高于对照组,差异有统计学意义(P<0.05);治疗A组患儿总有效率高于治疗B组,不良反应发生率低于治疗B组,差异有统计学意义(P<0.05)。结论阿奇霉素分散片治疗肺炎支原体感染致小儿过敏性咳嗽的临床疗效显著,可有效改善患儿临床症状,且不良反应少。
Objective To investigate the clinical efficacy of azithromycin in treating children with allergic cough caused by Mycoplasma pneumoniae infection. Methods Eighty children with allergic cough admitted in Linzhou People’s Hospital from July 2014 to July 2015 were selected as the treatment group and divided into treatment group A and treatment group B according to the random number table method. Another selected the same period Linzhou People’s Hospital admitted 80 cases of children with common respiratory tract infection as a control group. Treatment group B children to be treated by conventional methods, treatment of children with cough and antispasmodic group A macrolide drugs. The results of MP-Ig M assay in 3 groups were observed, and the clinical efficacy and adverse reactions in group A and B were observed. Results The positive rate of MP-Ig M in treatment group was higher than that in control group (P <0.05). The total effective rate in treatment group A was higher than that in treatment group B, and the incidence of adverse reactions was lower than that in treatment group B , The difference was statistically significant (P <0.05). Conclusion Azithromycin dispersible tablets in children with allergic cough caused by Mycoplasma pneumoniae infection have significant clinical curative effect, which can effectively improve the clinical symptoms of children with less adverse reactions.