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目的 探讨 Binswanger病 (BD)患者脑诱发电位改变的特点及其对 BD的诊断价值。方法 对6 0例 BD患者进行体感诱发电位 (SEP)、脑干听觉诱发电位 (BAEP)及视觉诱发电位 (VEP)检查 ,并与 30名同年龄组健康老人对照。结果 BD患者脑诱发电位异常率较高 ,SEP异常率为 96 .7% ,BAEP为 73.3% ,VEP为 6 6 .7% ,二项以上脑诱发电位异常率为 88.3% ,主要表现为 PL延长。痴呆组与轻、中度智能障碍组脑诱发电位比较无显著性差异 (P>0 .0 5 )。单纯智能障碍组 SEP表现为左侧 P2 7～ N6 0 PL延长 ;智能障碍伴运动迟缓组 SEP表现为 P1 4 ～ N2 0 PL 延长 ;智能障碍伴局限性神经功能障碍组 SEP表现为 P1 4 ～ N6 0 PL 均延长。结论 BD病人存在 EP多项异常 ,不同临床类型 ,EP异常特点不同
Objective To investigate the characteristics of brain evoked potentials in patients with Binswanger’s disease (BD) and its diagnostic value for BD. Methods Sixty BD patients were examined for somatosensory evoked potential (SEP), brainstem auditory evoked potentials (BAEP) and visual evoked potential (VEP), and compared with 30 healthy controls in the same age group. Results The abnormal rate of brain evoked potentials in patients with BD was higher than that in patients with BD. The abnormal rate of SEP was 96.7%, BAEP was 73.3%, VEP was 66.7%, and the abnormality rate of brain evoke potential was 88.3%. The main manifestations were PL prolongation . There was no significant difference in the brain evoked potentials between the dementia group and mild or moderate degree of intelligence impairment (P> 0.05). SEP in the simple intelligence impairment group was prolonged on the left side of P2 7 ~ N6 0 PL; SEP performance was delayed in P1 4 ~ N2 0 PL in patients with intellectual impairment and movement retardation group; SEP in the group of intellectual disturbance and limitation nerve dysfunction group was P1 4 ~ N6 0 PL are extended. Conclusion There are many abnormalities of EP in BD patients. Different clinical types and EP abnormalities have different characteristics