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本文比较观察了非肾炎型SLE和RA两种疾病的免疫状态,结果显示:(1)SLE非肾炎型病人血清补体水平与RA相比明显下降,RA与正常组比较CH_(50)稍有下降,C_2略有上升。(2)SLE非肾炎型病人E—RFC与RA相比有显著降低,而较RA细胞免疫水平与正常组相仿。(3)ANA检出率在非肾炎型SLE较高,而在RA较低,两者比较亦有显著性差异,相反,RF检出率在RA较高,而在非肾炎型SLE较低,两者比较亦有显著性差异。(4)非肾炎型SLE的CIC检出率高于RA,但两者无显著性差异。(5)非肾炎型SLE的LE细胞检出率显著高于RA。基于上述发现,作者认为检测补体水平特别是C_3的水平,同时参考自身抗体、细胞免疫和LE细胞检测结果,对上述两种疾病的鉴别诊断有指导意义。
This article comparatively observed the immune status of non-nephritic SLE and RA. The results showed that: (1) Serum complement levels in patients with SLE non-nephritis were significantly lower than those in RA, and CH_ (50) was slightly decreased in RA compared with normal controls , C_2 increased slightly. (2) The E-RFC of non-nephritis patients with SLE was significantly lower than that of RA, while the immunity of RA patients was similar to the normal group. (3) The detection rate of ANA is higher in patients with non-nephritic SLE, while in RA is lower, there is a significant difference between the two. On the contrary, the detection rate of RF is higher in RA and lower in non-nephritis SLE, There was also a significant difference between the two. (4) The detection rate of CIC in non-nephritic SLE was higher than that in RA, but there was no significant difference between them. (5) The detection rate of LE cells of non-nephritic SLE was significantly higher than that of RA. Based on the above findings, the author believes that the detection of complement levels, especially C_3 levels, and reference to autoantibodies, cellular immunity and LE cell test results, the differential diagnosis of the above two diseases is instructive.