论文部分内容阅读
天津医药杂志6卷10期(1964年10月号)901页发表了王文蔚同志的“评《临床药物手册》”,愿提出几点管见。一、书评中认为水杨酸钠配伍制酸剂用碳酸氢钠有缺点,近年来多“改用氢氧化铝或三硅酸镁等,不但减少水杨酸钠对胃肠道的刺激,且避免了碳酸氢钠的缺点。”水杨酸钠口服而遇胃酸后,释出水杨酸,对于胃黏膜有刺激作用,但不是对胃肠皆有刺激。用氢氧化铝或三硅酸镁与水杨酸钠配伍,也不是没有缺点的,此二药与水杨酸钠等量或半量内服后,氢氧化铝可致便秘,三硅酸镁能致腹泻。笔者认为,为了克服水杨酸钠在胃内分解的刺激
Tianjin Medical Journal 6 Volume 10 (October 1964) 901 pages published Comrade Wang Wenwei’s “review” of clinical drug manual “, would like to make a few comments. First, the book reviews that sodium salicylate with sodium bicarbonate antacid shortcomings, in recent years more ”to aluminum hydroxide or magnesium trisilicate, not only to reduce the stimulation of sodium salicylate gastrointestinal tract, and Avoid the shortcomings of sodium bicarbonate. "Sodium salicylate orally and in case of gastric acid release of salicylic acid, gastric mucosa have a stimulating effect, but not all stimulate the gastrointestinal. With aluminum hydroxide or magnesium trisilicate and sodium salicylate compatibility, is not without its drawbacks, the two drugs and sodium salicylate equal or half the amount of oral administration, aluminum hydroxide can cause constipation, magnesium trisilicate can cause diarrhea. In my opinion, in order to overcome the irritation of sodium salicylate decomposition in the stomach