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为探讨丙型肝炎病毒（ＨＣＶ）血清学分型与基因分型结果的一致性、可靠性和实用性，对基因型明确的５７例患者血清用ＥＩＡ 进行血清学分型，并与部分患者临床资料进行比较。结果显示，ＥＩＡ 检出型特异性抗体３２例（５６．１％ ），其中血清１型（相当于基因型Ⅰ，Ⅱ型）１５例（４６．９％ ），血清２型（相当于基因型Ⅲ、Ⅳ型）１０例（３１．２％ ），血清１，２型均阳性７例（２１．９％ ）。血清型与基因型符合率为７１．２％ （２３／３２）。据此认为ＨＣＶ 血清学分型法的灵敏性、特异性及实用性均不及基因分型法。
In order to investigate the consistency, reliability and practicability of the serological typing and genotyping results of hepatitis C virus (HCV), the sera of 57 patients with definite genotypes were serotyped with EIA and compared with clinical data of some patients Compare The results showed that there were 32 cases (56.1%) of EIA detected type antibodies, of which 15 cases (46.9%) were serotype 1 (corresponding to genotypes I and II), 2 serotypes Ⅲ, Ⅳ type) in 10 cases (31.2%), serum type 1 and 2 were positive in 7 cases (21.9%). The coincidence rate of serotype and genotype was 71.2% (23/32). Therefore, the sensitivity, specificity and practicability of HCV serotyping method are not as good as genotyping.