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对３１９例乳癌根治术施行了高位硬膜外阻滞麻醉。结果：阻滞完善者２７３例（占８５．５９％），阻滞不全者４６例（占１４．４１％）经加静脉复合麻醉完成手术。其中有７例发生轻度的呼吸困难，术中心率和血压无明显变化。结论：对于中青年乳癌根治术患者选择１．２％～１．４％利多卡因或０．３％～０．４％布匹卡因行高位硬膜外阻滞麻醉，首次剂量１３～１５ｍｌ是安全、有效的。
High epidural anesthesia was performed on 319 cases of radical mastectomy. Results: 273 cases (85.59%) were obstructively improved, and 46 cases (14.41%) were incompletely agglutinated. Among them, 7 cases had mild dyspnea and no significant changes in the surgical center rate and blood pressure. Conclusion: For young and middle-aged patients undergoing radical mastectomy, 1.2%-1.4% lidocaine or 0.3%-0.4% bupivacaine is selected for high epidural anesthesia. The first dose of 13-15ml is Safe and effective.