The Effect of U50488 on the Cardiac Rhythm and Intracellular Calcium in the Rat Heart.

• 作 者: 张为民 辛达临 黄德明
• 机 构: RespiratoryDepartment,LiuHuaQiaoHospital,Guangzhou510010,PRChina,DepartmentofPhysiology,InstituteofC
• 出 处: South China Journal of Cardiology
• 发表日期: 2000年1期
• 关键词: K-opioid receptor ARRHYTHMIA Isolated rat HEART PHOSPHOLIPASE C INTRACELLULAR CA

The effect of U50488, a selective K-opioid receptor agonist, on cardiac rhythm in the isolated perfused rat heart and intracellular calcium ([Ca2+] i) in the single ventricular myocyte were studied. The results showed that U50488 can induce arrhythmias do