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血清 CK 同功酶 MM 经等电点聚焦分解成一种5条区带的图象,该图象在心肌梗塞发作后逐渐变化而成。在经受冠状动脉旁路手术的患者中也证实了类似的发现。上述两种病例中,两个 CK-MB 亚带的演变曾被研究。作者发现三个电泳区带(CK-MM、等电点7.10;CK-MM_1、等电点6.88;CK-MB_1、等电点5.61)在心肌梗塞早期所收集的血清电泳图象中居于优势,但随后数小时即迅速消失;而那些加快了电泳迁移率的区带(MM_2、等电点6.7;MM_3、等电点6.45;MM_4等电点6.25;MB_2、等电点5.34)却迅速增加。在急性心肌梗塞观察期的末期,MM_3永远是主要区带,血清总 CK 峰值后36
Serum CK isoenzyme MM is resolved by isoelectric focusing into a 5-zone image that gradually changes after the onset of a myocardial infarction. Similar findings were also confirmed in patients undergoing coronary artery bypass surgery. In both cases, the evolution of two CK-MB subbands has been studied. The authors found that the three electrophoresis bands (CK-MM, isoelectric point 7.10; CK-MM_1, isoelectric point 6.88; CK-MB_1, isoelectric point 5.61) predominated in the serum electrophoresis images collected in the early stages of myocardial infarction, But rapidly disappeared in the next few hours; however, those zones that accelerated the electrophoretic mobility (MM_2, isoelectric point 6.7; MM_3, isoelectric point 6.45; MM_4 isoelectric point 6.25; MB_2, isoelectric point 5.34) rapidly increased. At the end of acute myocardial infarction observation period, MM_3 is always the main zone, and the peak value of serum total CK