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目的探讨不同他汀类药物对早发冠心病急性心肌梗死患者近期的临床疗效。方法选取2012年1月-2014年12月我院收治的早发冠心病急性心肌梗死患者80例,随机分为对照组同研究组各40例,对照组患者使用阿托伐他汀治疗,研究组患者使用瑞舒伐他汀治疗,对比两组患者的治疗结果;结果两组患者治疗之后,总胆固醇、空腹血糖、C敏反应蛋白以及低密度脂蛋白等指标均显著下降,同治疗前对比差异有统计学意义(P<0.05);同时两组患者治疗后总胆固醇、空腹血糖、C敏反应蛋白以及低密度脂蛋白等指标差异无统计学意义(P>0.05)。结论不同他汀类药物对早发冠心病急性心肌梗死患者近期的临床疗效均比较理想,值得在临床上推广应用。
Objective To investigate the short-term clinical efficacy of different statins on patients with premature coronary heart disease with acute myocardial infarction. Methods From January 2012 to December 2014, 80 patients with acute myocardial infarction with premature coronary heart disease admitted to our hospital were randomly divided into control group (40 cases) and research group (40 cases). Patients in the control group were treated with atorvastatin. The study group The patients were treated with rosuvastatin, and the results of treatment were compared between the two groups. Results After treatment, the total cholesterol, fasting blood glucose, C-reactive protein and low density lipoprotein were significantly decreased (P <0.05). There was no significant difference in total cholesterol, fasting blood glucose, C-reactive protein and low density lipoprotein between the two groups after treatment (P> 0.05). Conclusions Different statins have good clinical efficacy in patients with premature coronary heart disease with acute myocardial infarction, and are worth popularizing in clinic.