论文部分内容阅读
目的观察长托宁和阿托品治疗急性有机磷农药中毒患者疗效比较。方法近3年我院共治疗急性有机磷中毒145例,随机分为长托宁组及阿托品组,两组均伍用氯解磷定治疗,观察两组治疗的临床疗效。结果长托宁组73例,死亡3例。其中2例因口服氧化乐果200ml,1例口服对硫磷150ml,就诊时间延误。其余70例治愈。阿托品组72例,死亡13例,其中2例因多器官功能衰竭死亡,其余8例因阿托品用量过大,突发呼吸衰竭死亡。3例为氧化乐果中毒72h后出现中间综合征至呼吸肌麻痹、呼吸衰竭死亡。结论长托宁组在住院时间、中毒症状消失及毒副作用等方面明显优于阿托品组,具有可比性。
Objective To observe the efficacy of the combination of pendimethalin and atropine in patients with acute organophosphorus pesticide poisoning. Methods A total of 145 cases of acute organophosphorus poisoning were treated in our hospital in the recent 3 years. They were randomly divided into a long-acting group and atropine-treated group. Both groups were treated with chlorpheniramine, and the clinical effects of the two groups were observed. Results Long Tuoning group of 73 cases, 3 patients died. Two of them were orally administered omethoate 200ml, one oral paracetamol 150ml, treatment time was delayed. The remaining 70 cases were cured. 72 cases of atropine group, 13 died, of which 2 died of multiple organ failure, and the remaining 8 cases of atropine overdose, sudden respiratory failure death. 3 cases of omethoate poisoning after 72h appeared respiratory syndrome respiratory paralysis, respiratory failure and death. Conclusion The long-acting group is superior to the atropine group in hospitalization time, the disappearance of symptoms of poisoning and toxic side effects, comparable.