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目的研究高原地区伴有高尿酸血症的高血压患者与颈动脉的粥样斑块的相关性。方法选取136例高血压患者,按照血尿酸的水平对其进行分组,分为高尿酸血症组(观察组),49例患者,另一组为尿酸正常组(对照组),87例患者,使用高频的超声探头对两组患者进行颈部动脉的检测,查看有无粥样斑块,并进行相关性分析。结果在观察组的49例患者当中有37例检测出了斑块,比例达到75.7%;在对照组的87例患者当中有24例患者检测出了斑块,比例是27.6%,两组的结果对比有显著性差异,存在统计学意义(P<0.05)。同时,血尿酸的水平越高,患者颈部动脉的粥样斑块也越厚,两者之间有明显的相关性。结论伴随高尿酸血症的高血压患者比尿酸正常的高血压患者,其颈部动脉更容易出现粥样斑块,而且患者的尿酸水平越高,其颈动脉的粥样斑块越严重,两者有非常显著的相关性。
Objective To investigate the association between carotid atherosclerosis and hypertension in patients with hyperuricemia in the plateau. Methods A total of 136 hypertensive patients were selected and divided into hyperuricemia group (observation group), 49 patients and normal uric acid group (control group). 87 patients, The use of high-frequency ultrasound probe on the two groups of patients with neck artery detection, check for atherosclerotic plaque, and correlation analysis. RESULTS: Of the 49 patients in the observation group, 37 were plaques detected, accounting for 75.7% of the patients in the observation group; 24 of the 87 patients in the control group had plaques detected, with a proportion of 27.6%. The results for both groups The difference was statistically significant (P <0.05). In the meantime, the higher the level of serum uric acid, the thicker the atherosclerotic plaque of the neck artery of patients, and the obvious correlation between the two. Conclusions Hypertensive patients with hyperuricemia are more likely to have atherosclerotic plaques in hypertensive patients with normal uric acid than those with normal uric acid. The higher the level of uric acid in patients with carotid artery plaque is, There is a very significant correlation.