论文部分内容阅读
目的总结年轻乳腺恶性肿瘤患者的临床病理特征及超声声像图特征。方法回顾性分析2007年1月至2008年12月在本院进行手术并被病理证实为乳腺恶性肿瘤的40例年轻患者(≤35岁)的临床病理资料与超声影像资料。结果 40例患者平均年龄(29.88±5.12)岁。14例患者(35%)有肿物短期内快速生长病史。3例患者为妊娠哺乳期乳腺癌。35例患者(共40个恶性病灶)接受超声检查,超声漏诊5个病灶,误诊4个病灶,31个病灶在术前超声诊断为恶性肿瘤,诊断准确率为77.5%。超声声像图主要表现为形态不规则(97.1%)、边界不清(82.9%)、内部回声不均匀(97.1%)、微小钙化常见(74.3%)、血流丰富(Ⅱ~Ⅲ级80.0%)。15例(37.5%)患者采用保乳术,4例(10.0%)采用乳房单纯切除术,21例(52.5%)采用乳腺癌改良根治术。病理类型以浸润性导管癌最常见,占67.5%(27/40)。22例(55%)患者有腋窝淋巴结转移。对40例患者平均随访(64.08±5.87)个月,8例(20%)患者出现复发或转移。平均复发时间为术后(17.17±12.02)个月。结论年轻乳腺恶性肿瘤患者的肿瘤复发率高,淋巴结转移率高,超声声像图表现多样。
Objective To summarize the clinicopathological characteristics and ultrasonographic features of young patients with breast cancer. Methods The clinical data and ultrasound imaging data of 40 young patients (≤35 years) who underwent surgery in our hospital from January 2007 to December 2008 and were confirmed as pathologically confirmed breast cancer were retrospectively analyzed. Results The average age of 40 patients (29.88 ± 5.12) years. Fourteen patients (35%) had a history of rapid tumor growth in the short term. Three patients were breast-feeding during pregnancy and breast cancer. Thirty-five patients (40 malignant lesions) underwent ultrasonography. Five lesions were misdiagnosed by ultrasound, 4 lesions were misdiagnosed, and 31 lesions were diagnosed as malignant tumors by preoperative ultrasonography. The diagnostic accuracy was 77.5%. Ultrasonography mainly showed irregular shape (97.1%), unclear border (82.9%), internal echo unevenness (97.1%), common microcalcification (74.3%) and rich blood flow ). Fifteen patients (37.5%) underwent conservative surgery, 4 (10.0%) underwent simple mastectomy and 21 (52.5%) underwent modified radical mastectomy. Pathological type of invasive ductal carcinoma is the most common, accounting for 67.5% (27/40). Twenty-two patients (55%) had axillary lymph node metastases. The average follow-up of 40 patients (64.08 ± 5.87) months, 8 patients (20%) patients with recurrence or metastasis. The average recurrence time was (17.17 ± 12.02) months after operation. Conclusion The incidence of tumor recurrence in young patients with breast cancer is high, the rate of lymph node metastasis is high, and the ultrasonography is diverse.