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目的:探讨早发型重度子痫前期期待治疗对母儿预后的影响。方法:对该院2000～2008年92例早发型重度子痫前期患者进行回顾性分析。根据其入院孕周不同分为3组:即Ⅰ组(24～28周),Ⅱ组(28～32周),Ⅲ组(32～34周)。根据其治疗时间的长短又分为4组:即A组(≤48 h),B组(48 h～7天),C组(8～14天),D组(≥15天)。结果:早发型重度子痫前期发病孕周越早,患者并发症的发生率越高,但Ⅰ、Ⅱ、Ⅲ组差异无统计学意义(P>0.05),新生儿死亡率和围生儿死亡率随着发病孕周的延长而显著降低(P<0.05)。结论:早发型重度子痫前期严重影响母儿预后,适当的期待治疗有助于改善母儿预后,降低围生儿死亡率。
Objective: To investigate the effect of expectant treatment of early onset severe preeclampsia on the prognosis of maternal and child. Methods: 92 cases of early-onset severe preeclampsia in our hospital from 2000 to 2008 were analyzed retrospectively. According to their different gestational age, they were divided into three groups: group Ⅰ (24-28 weeks), group Ⅱ (28-32 weeks) and group Ⅲ (32-34 weeks). According to the length of treatment, the patients were divided into 4 groups: group A (≤48h), group B (48h-7d), group C (ranged from 8 to 14d) and group D (≥15d). Results: The earlier the gestational age in early onset severe preeclampsia was, the higher the incidence of complications was. However, there was no significant difference between Ⅰ, Ⅱ and Ⅲ groups (P> 0.05). Neonatal mortality and perinatal mortality The rate of pregnancy decreased significantly with gestational age (P <0.05). Conclusion: Early onset severe preeclampsia has a serious impact on the prognosis of maternal and infant. Appropriate expectant treatment can improve maternal and child prognosis and reduce perinatal mortality.