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受试者为经β阻滞剂和/或钙拮抗剂治疗仍有高度稳定型心绞痛的47例病人,冠脉造影均有单支狭窄>70%,年龄≤70岁,病程≥6个月,近3个月内无心肌梗塞。A 组25例原先使用β阻滞剂(14例使用美托洛尔100mg,bid;另11例使用其它4种β阻滞剂之一),其中16例并用钙拮抗剂(12例使用硝苯啶20mg,tid;另4例使用维拉帕米或地尔硫革)。B 组22例原先使用钙拮抗剂(硝苯啶、维拉帕米和地尔硫草)。除心绞痛发作时含服硝酸甘油外,突然停用所
Subjects were 47 patients with highly stable angina pectoris who were treated with beta blockers and / or calcium antagonists. All patients underwent coronary angiography with> 70% single stenosis, age ≤70 years, duration ≥6 months, No myocardial infarction within 3 months. Of the 25 patients in group A, beta blockers were previously used in 14 patients (metoprolol 100 in 14 patients and one in 4 other β blockers in 11 patients), 16 of them were treated with calcium antagonists (nifedipine Pyridine 20mg, tid; the other 4 cases with verapamil or diltiazem). Twenty-two patients in group B used calcium antagonists (nifedipine, verapamil, and diltiazem). In addition to angina attacks containing nitroglycerin, the sudden stop