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目的探讨氟喹诺酮类药物的不良反应与合理使用。方法回顾性分析42例使用氟喹诺酮类药物发生不良反应的特点与相关因素。结果不良反应主要累及消化系统、神经系统、皮肤等。静脉给药方式时不良反应发生率较高。结论使用氟喹诺酮类药物时,要严格掌握适应证和患者体质,选择适宜的给药方式,密切观察并及时处理,注意药物使用的合理性可以有效预防和减少不良反应的发生率。
Objective To investigate the adverse reactions and rational use of fluoroquinolones. Methods A retrospective analysis of 42 patients with fluoroquinolones adverse reactions characteristics and related factors. Results adverse reactions mainly involving the digestive system, nervous system, skin and so on. The incidence of adverse reactions when intravenous administration is higher. Conclusion When using fluoroquinolones, it is necessary to strictly control the indications and patient’s physique, select the appropriate mode of administration, observe closely and timely treatment, pay attention to the rationality of drug use can effectively prevent and reduce the incidence of adverse reactions.