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本文介绍了在冈比亚的苏库塔村进行的一次用大剂量〔4万蚀斑形成单位(PFU〕的Edmonston-Zagreb(EZ)麻疹疫苗免疫接种4月龄婴儿的试验,并与常规的6000半数组织培养感染量(TCID_(50))的Schwarz(SW)麻疹疫苗免疫接种9月龄婴儿的效果进行了比较.试验结果如下:1.接种疫苗时的麻疹抗体水平:EZ组(110人)和SW组(112人)分别有66.4%和12.5%的儿童可检出血凝抑制(HAI)抗体(>100mIU/ml).两组的抗体几何平均滴度
This article describes a trial of 4-month-old infants immunized with a large dose of 40,000 plaque-forming units (PFU) of the Edmonston-Zagreb (EZ) measles vaccine in the village of Sukhothai Gambia and compared with the conventional 6000 half The results of immunization of 9-month-old infants who received Schwarz (SW) measles vaccine with tissue culture infection amount (TCID 50) were compared as follows: 1. Measles antibody levels at vaccination: EZ group (110) and The hemagglutination inhibition (HAI) antibody (> 100 mIU / ml) was detectable in 66.4% and 12.5% of children in the SW group (112), respectively. The geometric mean titers