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基因多态性对疾病临床表型影响的研究是使临床医学最终走向个体化的基础。本研究以我国肾小球疾病中最常见的 Ig A肾病 ( Ig AN)、狼疮性肾炎 ( LN)和糖尿病肾病为重点 ,围绕血管紧张素转换酶基因、白细胞介素 - 1受体拮抗剂基因、葡萄糖转运蛋白 ( GLUT1 )和胰岛素受体底物 -
The study of the impact of genetic polymorphism on the clinical phenotype of the disease is the basis for the end-to-individualization of clinical medicine. In this study, we focused on the most common IgA nephropathy (IgAN), lupus nephritis (LN) and diabetic nephropathy in glomerular diseases in China, and focused on the angiotensin converting enzyme gene, interleukin - 1 receptor antagonist gene , Glucose transporter (GLUT1) and insulin receptor substrate -