75874名居民近亲婚配遗传效应的研究

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本文通过对象山县二镇10乡104村75874名居民的调查,发现有17种类型的近亲婚配共603对,近亲婚配率2.85%、F16.35×10~4,其中三级亲属近亲结婚占85.4%。近亲夫妇的自然流产率、子女20岁前早死率、遗传和先天畸形的患病率为2.91%、7.49%,53.46‰;非近亲组为0.79%、4.72%、13.21‰,有非常显著的差异。在半岛和海岛组间唯子女20岁前早死率海岛组明显高于半岛组,尤其在四个年代和五十年代,经分析与其地理位置无关,但与海岛的交通及卫生事业相对落后有关。鉴于在八十年代尚有1.7%的近亲婚配率,作者认为,在贯彻落实婚姻法时,当前的工作重点还应放在严禁三级亲属近亲婚配方面。 Based on the survey of 75,874 residents in 104 villages of 10 townships in two townships of Shanxian County, we find that there are 603 pairs of inbreeding with 17 types, the relative marriage rate is 2.85%, F16.35 × 10 ~ 4, of which, 85.4%. The rates of spontaneous abortion of their close relatives, the premature mortality rates of 20 children before birth, the genetic and congenital malformations of their children were 2.91%, 7.49% and 53.46 ‰ respectively, while those of non-close relatives were 0.79%, 4.72% and 13.21 ‰, with significant differences . In the peninsular and island groups, the number of premature childbirth of the only child before the age of 20 was significantly higher than that of the peninsula. Especially in the four years and the 1950s, the analysis had no relation with its geographical location but was related to the relative backwardness of the island’s transportation and health. In view of the 1.7% of kinship rates in the 1980s, the author believes that in the implementation of the Marriage Law, the current emphasis should be placed on the third-degree relatives’ close relatives marriage.
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