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目的:探讨一氧化碳中毒迟发性脑病(DEAcMP)的临床特征。方法:回顾性分析DEACMP48例患者的病历资料。结果:DEACMP既往有心脑血管病史者38例;一氧化碳环境暴露时间≥6小时者34例;临床表现多样:淡漠、谵妄、痴呆、大小便失禁、肢体肌张力异常、肢体瘫痪、癫痫等;治疗后临床痊愈9例,好转25例,总有效率70.83%。结论:既往心脑血管病史、一氧化碳环境暴露时间是影响DEACMP预后的重要危险因素;DEACMP临床表现多样;及时、足疗程的高压氧治疗可最大限度促进患者康复。
Objective: To investigate the clinical features of delayed-onset carbon monoxide poisoning (DEAcMP). Methods: Retrospective analysis of 48 cases of DEACMP patients medical records. Results: DEACMP had previous history of cardiovascular and cerebrovascular diseases in 38 cases; carbon monoxide environmental exposure time of 6 hours or more in 34 cases; clinical manifestations: indifference, delirium, dementia, incontinence, abnormal limb muscle tension, limb paralysis, epilepsy; treatment After clinical recovery in 9 cases, improved in 25 cases, the total effective rate was 70.83%. CONCLUSION: Previous cardiovascular and cerebrovascular diseases, exposure time of carbon monoxide environment are important risk factors affecting the prognosis of DEACMP. The clinical manifestations of DEACMP are diverse. Hyperbaric oxygen therapy can provide maximal stimulation of patients’ recovery after DEACMP treatment.