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目的探讨视网膜对比敏感度对伴与不伴视网膜病变的糖尿病患者视觉功能评价的意义。方法为回顾性系列病例研究。使用RM-800对比敏感度仪测量62例(104眼)2型糖尿病患者和对照组54例(54眼)不同空间频率1.8,3,6,12,18和24周/度(c/d)的视网膜对比敏感度。根据眼底荧光血管造影情况把处于非增生期糖尿病性视网膜病变(NPDR)的糖尿病患者分成3组:DM1为无眼底改变、DM2为仅有微动脉瘤改变、DM3为有微动脉瘤和硬性渗出改变。结果糖尿病各组的对比敏感度在各频段均有下降(P<0.01);各组之间差异有统计学意义(P<0.01);DM3下降最明显,DM2次之,DM1下降轻微。结论在伴与不伴视网膜病变的糖尿病患者视网膜对比敏感度均有下降,对比敏感度可以作为糖尿病对眼底影响的重要信息。
Objective To investigate the significance of retinal contrast sensitivity in evaluating the visual function of diabetic patients with and without retinopathy. Methods for retrospective series of case studies. In 54 cases (54 eyes) of 62 cases (104 eyes) with type 2 diabetes mellitus and control group, different spatial frequencies of 1.8, 3, 6, 12, 18 and 24 weeks / Retinal contrast sensitivity. According to fundus fluorescein angiography in non-proliferative diabetic retinopathy (NPDR) of diabetic patients are divided into three groups: DM1 no fundus changes, DM2 only microaneurysm changes, DM3 with micro-aneurysms and hard exudate change. Results The contrast sensitivity of each group was decreased in all frequency groups (P <0.01). There was a significant difference between each group (P <0.01). The DM3 decreased most obviously, followed by DM2 and DM1 decreased slightly. Conclusions The contrast sensitivity of retina in diabetic patients with and without retinopathy has decreased, and contrast sensitivity can be used as an important information of the influence of diabetes on the fundus.