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为探讨肿瘤坏死因子与泌尿系感染的关系，我们应用双抗体夹心ELISA法检测了24例泌尿系感染患者血浆肿瘤坏死因子，并与30例健康人对照。结果发现：1、泌尿系感染患者血浆肿瘤坏死因子明显高于健康对照组（P＜0．05）；2、感染患者经治疗后，血浆肿瘤坏死因子恢复至正常水平；3、泌尿系统感染患者血浆肿瘤坏死因子活性变化与其它临床症状及尿液检查相一致。结果提示：肿瘤坏死因子参与炎症的病理过程。急性炎症时，应考虑细胞因子所起的作用。
To explore the relationship between tumor necrosis factor and urinary tract infection, we detected the plasma tumor necrosis factor (TNF) in 24 patients with urinary tract infection by double antibody sandwich ELISA and compared with 30 healthy people. The results showed that: 1, the plasma tumor necrosis factor in patients with urinary tract infection was significantly higher than that in the healthy control group (P <0.05); 2, after treatment, the plasma tumor necrosis factor returned to normal levels; 3, patients with urinary tract infections Changes in plasma tumor necrosis factor activity and other clinical symptoms and urine tests are consistent. The results suggest that tumor necrosis factor is involved in the pathological process of inflammation. Acute inflammation, should consider the role of cytokines.