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目的了解口服抗抑郁药的应用情况,探讨其使用特点及发展趋势。方法利用苏州大学附属第二医院计算机系统,统计分析了该院2005年至2009年使用抗抑郁药的品种、数量、消耗金额、用药频度及日费用金额等情况。结果口服抗抑郁药年消耗金额和用药频度(DDDs)呈逐年上升趋势(rs=1.000,P<0.01),其中选择性5-羟色胺(5-HT)再摄取抑制剂(SSRIs)在5年期间年消耗金额占总金额的80%以上,DDDs占总用药频度的65%以上。结论高效、副作用小的SSRIs抗抑郁药是临床药物治疗的首选。
Objective To understand the application of oral antidepressants and to explore the characteristics of their use and development trends. Methods The computer system of the Second Affiliated Hospital of Soochow University was used to statistically analyze the variety, quantity, consumption amount, frequency of medication and daily expense of antidepressants used in the hospital from 2005 to 2009. Results The annual consumption of oral antidepressants and DDDs increased year by year (rs = 1.000, P <0.01), and selective 5-HT reuptake inhibitors (SSRIs) During the annual consumption of more than 80% of the total amount, DDDs the total frequency of medication for more than 65%. Conclusion SSRIs antidepressants with high efficacy and low side effects are the first choice of clinical drug therapy.