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目的:探讨对神经母细胞瘤患儿实施药学监护的内容和意义。方法:临床药师通过对1例5岁儿童神经母细胞瘤术后进行奥沙利铂联合依托泊苷化疗的全程药学监护,以化疗药物合理应用、不良反应监测和预防、个体化用药方案的制定作为临床药师药学监护切入点。结果:临床药师通过医嘱审核发现并及时纠正错误,并对患儿实施骨髓抑制、神经毒性、消化道反应等不良反应的预防与监护,使患儿顺利度过了化疗期。结论:实施药学监护的过程中,临床药师及时有效的建议促进了肿瘤化疗患儿的合理用药。
Objective: To explore the content and significance of the implementation of pharmacy care in children with neuroblastoma. Methods: Clinical pharmacists through a 5-year-old children with neuroblastoma oxaliplatin combined with etoposide chemotherapy full course of pharmacy care, to the rational use of chemotherapy drugs, adverse reaction monitoring and prevention, the development of individualized drug program As a clinical pharmacist point of care. Results: The clinical pharmacist found out and corrected the mistakes in time through the examination of doctor ’s orders and carried out the prevention and monitoring of the adverse reactions such as myelosuppression, neurotoxicity and gastrointestinal reaction in the children so that the children successfully passed the chemotherapy period. Conclusion: In the process of implementing medical supervision, timely and effective suggestions of clinical pharmacists promote rational drug use in children with tumor chemotherapy.