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目的了解广东省外来流动人口血吸虫感染情况及病人的分布状况,为制定血吸虫病监测技术方案提供科学依据。方法于2005年6月至2007年7月在广东省分粤东、粤西、粤北、粤中4个区,每区按经济发展程度高、中、低各随机抽取2个共24个县(市、区)作为调查点;采用分层整群抽样调查外来流动人口分布情况;每个调查点按整群抽样原则抽取来自疫区的流动人口1000人,并对其采用胶体金渗滤法(DIGFA)检测血清中血吸虫抗体、病原学检查(kato-katz)进行确诊;统计分析外来流动人口城乡分布、来自疫区人口比例、血吸虫病患病率、血吸虫病确诊率等。结果共调查22个县(市、区),收集统计外来流动人口数6360505人,主要集中在粤中的珠江三角洲地区,占91.18%,当中主要是分布在农村地区和城乡结合部,占82%。外来流动人口中来自疫区的占19.49%(24777/127122),主要是15～49岁的人群,占98.92%。来自疫区人群血吸虫抗体阳性率为1.74%(228/13076),以15～39岁的人群较高(P<0.01);血吸虫抗体阳性者血吸虫病患病率为21.93%(50/228),调查人群总患病率即为0.38%(50/13076);血吸虫抗体阳性者病原确诊率为2.63%(6/228),即调查人群总确诊率为0.05%(6/13076)。结论推算在广东省的外来流动人口中可能有血吸虫病患者3万例以上,大部分患者是居住在粤中水网地带的农村地区或城乡结合部,可能将对该地区血防成果的巩固造成一定的威胁。
Objective To understand the prevalence of schistosomiasis and the distribution of patients in floating migrants in Guangdong Province, and to provide a scientific basis for developing a monitoring program of schistosomiasis. Methods From June 2005 to July 2007, Guangdong Province was divided into four districts of eastern Guangdong, western Guangdong, northern Guangdong and eastern Guangdong. Each district was randomly selected according to its high level of economic development, middle and low levels, (Cities and districts) as survey points; stratified cluster sampling to investigate the distribution of floating population; each survey point sampling population from affected areas in accordance with the principle of cluster sampling of 1,000 people, and its colloidal gold percolation method (DIGFA) for the detection of schistosome antibodies in serum and kato-katz for diagnosis. The distribution of urban and rural migrants was statistically analyzed. The proportion of the population from the affected areas, the prevalence of schistosomiasis and the diagnosis rate of schistosomiasis were calculated. Results A total of 2260 counties (cities and districts) were surveyed to collect 6,360,505 foreign migrants, mainly in the Pearl River Delta in Guangdong Province, accounting for 91.18% of the total. Among them, they were mainly distributed in rural areas and urban-rural areas, accounting for 82% . Among the migrant population, 19.49% (24777/127122) were mainly from the epidemic areas, mainly from 15 to 49 years old, accounting for 98.92%. The positive rate of schistosomiasis was 1.74% (228/13076) in the epidemic area, and was higher in the population aged 15-39 (P <0.01). The prevalence of schistosomiasis was 21.93% (50/228) The overall prevalence of the surveyed population was 0.38% (50/13076). The prevalence of schistosoma infection was 2.63% (6/228), that is, the total confirmed diagnosis rate was 0.05% (6/13076). Conclusions It is estimated that more than 30,000 schistosomiasis patients may be included in the migrant population in Guangdong Province. Most of the patients are rural areas or urban-rural areas living in the middle of the Guangdong-Zhongshui hydropower zone, which may result in the consolidation of blood-stricken areas in the area. Threats.